Patients who have experienced a stroke as a result of
blockages of the arteries in the brain have better outcomes with the use of
balloon-guided catheter surgery as compared to having a conventional guided
catheter procedure, according to the findings of a study published in the Journal of NeuroInterventional Surgery.
Clot retrieval is typically the treatment for large vessel
occlusions (LVO), which are strokes that result from a blockage in one of the
major arteries of the brain. Treatment options include use of a
balloon-guided catheter or a conventional guided catheter.
Researchers from Boston University School of Medicine
(BUSM), Mercy Health Neuroscience Institute of Toledo, University of Toledo and
several other centres compared two groups of patients. In one group, patients
experienced a LVO stroke and underwent treatment with a stent with a
balloon-guided catheter. During clot retrieval, the balloon on the guide
catheter was temporarily inflated in the carotid artery to stop blood flow as
the clot was being removed. In the second group, patients had a LVO stroke and
underwent treatment with a stent retriever using a conventional guide catheter.
“When we compared both groups, patients who had
balloon-guided catheter had better restoration of blood flow scores and better
clinical outcomes,” explained corresponding author Thanh
Nguyen, MD, associate professor of neurology at BUSM and director,
Interventional Neuroradiology and Interventional Neurology at Boston Medical
“Achieving complete or near complete blood flow is the goal
to restore strength, language, coordination, reflexes and
sensation to patients suffering from ischemic stroke,” said senior author
Osama Zaidat, MD, who established the TRevo Acute Ischemic Stroke Thrombectomy
“Stopping arterial flow is an important step that can
improve restoration of blood flow, reduce the number of blood clot emboli to a
new area and potentially improve clinical outcome,” added co-author Mohamad
Abdalkader, MD, assistant professor of radiology at BUSM and interventional
neuroradiologist at BMC.
“Our study adds to the growing body of evidence that
highlights the potential of balloon-guide catheters to improve stroke patient
outcomes. Future studies are necessary to fully understand the role of this
technology in a larger patient population,” said co-author Alicia Castonguay,
PhD, assistant professor in the College of Medicine and Life Sciences at The
University of Toledo.
T, et al. Effect of balloon guide catheter on clinical outcomes and reperfusion
in Trevo thrombectomy. Journal of
NeuroInterventional Surgery. Published 2 February 2019.